flashcards_hus
Which specialists should be consulted for Haemolytic Uraemic Syndrome (HUS)?
Nephrology and haematology specialists.
What is the recommended management for children with the typical presentation of HUS?
Children with the typical presentation should be admitted.
What are the supportive management steps for HUS?
Monitor urine output and fluid balance, maintain adequate hydration status with IV isotonic crystalloids, monitor blood pressure, provide red cell transfusion if anaemic, avoid antibiotics, anti-diarrhoeals, narcotic opioids, and NSAIDs.
What should be avoided in the management of diarrhoea-associated HUS (D+ HUS)?
The use of antibiotics can worsen the disease.
How should blood pressure be managed in HUS?
Blood pressure should be monitored and treated if elevated using calcium channel blockers (CCBs). ACE inhibitors should be avoided as they can reduce renal perfusion.
What should be done if the patient with HUS is anaemic?
Red cell transfusion is needed.
What percentage of HUS patients will require dialysis in the acute phase?
50% of patients.
What is the management for irreversible renal failure in HUS?
Renal transplant will be needed if irreversible renal failure has occurred.
What is necessary for long-term follow-up in HUS patients?
Long-term follow-up is necessary due to the risk of persistent proteinuria, development of hypertension, and progressive CKD.
What characterizes atypical HUS and what is its prognosis?
Atypical HUS has no diarrhoeal prodrome, may be familial, frequently relapses, and has a high risk of hypertension and progressive CKD with a high mortality.
What additional treatment is required for thrombotic thrombocytopenic purpura in the context of HUS?
Plasmapheresis is required.
