VACCINE PREVENTABLE DISEASES Flashcards
what are the variations of diphtheria, tetanus, and pertussis?
TdaP
DTaP
endotoxin producing bacteria
5-10% mortality rate
diphtheria toxoid
-16 units in primary series; 2 units in adult booster
diphtheria
toxin producing bacteria
high fatality rate
tetanus toxoid
-give every 10 yrs
affect of overimmunization?
tetanus
can result in hypersensitivity immune complex reaction
starts with non specific respiratory symptoms that progress to paroxysmal cough with whoop
infants are susceptible
pertussis vaccination
bordetella pertussis
this pertussis vaccine contains toxin and some cell parts
acellular
this pertussis vaccine contains all cell components and toxin
adr-local reactions, fever, febrile seizures
whole cell
what diphtheria, tetanus, and pertussis combination is for use in patients > 7 yrs old
DTaP
what diphtheria, tetanus, and pertussis combination is for use in patients 7 yrs or older
Tdap
encapsulated bacterial infection
was the leading cause of invasive bacterial disease in children
first of conjugate vaccines
unimmunized can be immunized
not for patients with HIV
Haemophilis influenza type b (Hib)
contagious virus
not chronic
fecal oral route, person to person, increased liver enzymes
peds-12-23 m
adults-edemic areas, gay sex, drug users, clotting factors
hepatitis A
blood, intimate contact, skin lesions, mucosal surfaces
fever, headache, weakness
universal vaccine to eliminate perinatal transmission
peds-3 dose series, 0,1, 6-12 m
adults-hepB single antigen: 0,1,6-12 m; comb with HepA: 0,1,6 mon
hepatitis B
aim for hep B schedule with infected momz?
infants of HepB+mons should receive HBIG with Hep B vaccine
most common sexually transmitted infection?
which ones cause genital warts? cervical cancer?
HPV
6/11
16/18
contagious respiratory virus (types A/B) many subtypes
vaccine component different each year
influenza
name this meningococcal disease?
rapid onset illness, medical emergency
10% mortality rate
10% morbidity rate
5 serotypes (A,B,C,Y and W 135)
neisseria meningitidis
name this meningococcal disease?
disease causing strain not covered in quadrivalent vaccine products
per ACIP, low burden of disease limits recommendation routine vaccination
meningococcus B
what is the MMR vaccine?
measles
mumps
rubella
MMR vaccine for this disease:
highly contagious, airborne, direct contact
encephalitis, pneumonia, death
outbreak in california
measles
MMR vaccine for this disease:
airborne, direct contact
meningitis, encephalitis, inflammation of testicles or ovaries, deafness
mumps
MMR vaccine for this disease:
rash, fever, swollen lymph nodes
preg problems (miscarriage, stillbirth, premature delivery)
rubella
oral/fecal routes, in GI and invades bloodstream and CNS, sheds from GI after infection
fever, sore throat, nausea, headache, paralysis
- IPV (Salk)
- OPV (Sabin)
poliovirus
leading cause of infantile/childhood vomitting and diarrhea
oral/fecal
diarrhea, fever, vomitting
severe diarrhea, dehydration
rotavirus
air, direct contact
rash, fatigue, headache, fever
infected blisters, pneumonia, encephalitis
vaccine products are live virus
varicella
reactivation of VZV infection
unilateral vesicular rash
shingles is not transmissible, may transmit VZV to another to cause chicken pox
vaccine components
- lyophilized recombinant VZV glycoprotein E
- AS01 adjuvant
- measure of efficacy
HZVvaccine
herpes zoster virus (HZV)
