VACCINE PREVENTABLE DISEASES

Question 1

what are the variations of diphtheria, tetanus, and pertussis?

Answer 1

TdaP

DTaP

Question 2

endotoxin producing bacteria

5-10% mortality rate

diphtheria toxoid
-16 units in primary series; 2 units in adult booster

Answer 2

diphtheria

Question 3

toxin producing bacteria

high fatality rate

tetanus toxoid
-give every 10 yrs

affect of overimmunization?

Answer 3

tetanus

can result in hypersensitivity immune complex reaction

Question 4

starts with non specific respiratory symptoms that progress to paroxysmal cough with whoop

infants are susceptible

pertussis vaccination

Answer 4

bordetella pertussis

Question 5

this pertussis vaccine contains toxin and some cell parts

Answer 5

acellular

Question 6

this pertussis vaccine contains all cell components and toxin

adr-local reactions, fever, febrile seizures

Answer 6

whole cell

Question 7

what diphtheria, tetanus, and pertussis combination is for use in patients > 7 yrs old

Answer 7

DTaP

Question 8

what diphtheria, tetanus, and pertussis combination is for use in patients 7 yrs or older

Answer 8

Tdap

Question 9

encapsulated bacterial infection

was the leading cause of invasive bacterial disease in children

first of conjugate vaccines

unimmunized can be immunized

not for patients with HIV

Answer 9

Haemophilis influenza type b (Hib)

Question 10

contagious virus

not chronic

fecal oral route, person to person, increased liver enzymes

peds-12-23 m
adults-edemic areas, gay sex, drug users, clotting factors

Answer 10

hepatitis A

Question 11

blood, intimate contact, skin lesions, mucosal surfaces

fever, headache, weakness

universal vaccine to eliminate perinatal transmission

peds-3 dose series, 0,1, 6-12 m
adults-hepB single antigen: 0,1,6-12 m; comb with HepA: 0,1,6 mon

Answer 11

hepatitis B

Question 12

aim for hep B schedule with infected momz?

Answer 12

infants of HepB+mons should receive HBIG with Hep B vaccine

Question 13

most common sexually transmitted infection?

which ones cause genital warts? cervical cancer?

Answer 13

HPV

6/11
16/18

Question 14

contagious respiratory virus (types A/B) many subtypes

vaccine component different each year

Answer 14

influenza

Question 15

name this meningococcal disease?

rapid onset illness, medical emergency

10% mortality rate
10% morbidity rate

5 serotypes (A,B,C,Y and W 135)

Answer 15

neisseria meningitidis

Question 16

name this meningococcal disease?

disease causing strain not covered in quadrivalent vaccine products

per ACIP, low burden of disease limits recommendation routine vaccination

Answer 16

meningococcus B

Question 17

what is the MMR vaccine?

Answer 17

measles
mumps
rubella

Question 18

MMR vaccine for this disease:

highly contagious, airborne, direct contact

encephalitis, pneumonia, death

outbreak in california

Answer 18

measles

Question 19

MMR vaccine for this disease:

airborne, direct contact

meningitis, encephalitis, inflammation of testicles or ovaries, deafness

Answer 19

mumps

Question 20

MMR vaccine for this disease:

rash, fever, swollen lymph nodes

preg problems (miscarriage, stillbirth, premature delivery)

Answer 20

rubella

Question 21

oral/fecal routes, in GI and invades bloodstream and CNS, sheds from GI after infection

fever, sore throat, nausea, headache, paralysis

• IPV (Salk)
• OPV (Sabin)

Answer 21

poliovirus

Question 22

leading cause of infantile/childhood vomitting and diarrhea

oral/fecal

diarrhea, fever, vomitting

severe diarrhea, dehydration

Answer 22

rotavirus

Question 23

air, direct contact

rash, fatigue, headache, fever

infected blisters, pneumonia, encephalitis

vaccine products are live virus

Answer 23

varicella

Question 24

reactivation of VZV infection

unilateral vesicular rash

shingles is not transmissible, may transmit VZV to another to cause chicken pox

vaccine components

• lyophilized recombinant VZV glycoprotein E
• AS01 adjuvant
• measure of efficacy

HZVvaccine

Answer 24

herpes zoster virus (HZV)