AMINOPENICILLINS/OTHERS Flashcards
what are the examples?
amoxicillin
ampicillin
good against?
also, against what gram negative species?
strep spp
listeria monocytogenes
escherichia, shigella, salmonella
resistance due to?
beta lactamases, narrow spectrum
DOC for infections caused by penicillin susceptible Enterococcus spp infections
IV ampicillin
poor coverage over?
SPACE
serratia pseudomonas acinetobacter citrobacter enterobacter
ampicillin dosing, IV or oral
types of infections?
IV
moderate to serious infections
endocarditis, meningitis, bacteremia
amoxicillin dosing, IV or oral
types of infections?
oral
mild-moderate infections
sinusitis, otitis media, pharyngitis
common adverse drug reactions vs anaphylaxis?
diarrhea, nausea
anaphylaxis
thrombocytopenia
SJS
what are the penicillin/beta lactamase inhibitors studied?
amp-sulbactam
amo-clavulanate
piperacillin-tazobactam
penicillin/beta lactamase inhibitors are good against?
MSSA, enteric GNRs, bacteroides spp
*broad spectrum
only this penicillin/beta lactamase inhibitor has activity against acinetobacter baumannii?
route?
infection type?
amp-sulbactam
IV
moderate to severe infections
amoxicillin-claculanate,
route?
infection type?
PO
mild to moderate infections
less severe infections
otitis media
pharyngitis
tonsillitis
what are the Antipseudomonal penicillins?
piperacillin-tazobactam
what does the Antipseudomonal penicillin tazobactam act as?
route?
uses?
beta lactamase inhibitor and leads to increased stability of piperacillin against class A B-lactamases
IV only
moderate serious infections
SSTI
Pneumonia
gram negative non fermenting, motile bacillus
produces biofilm
non fastidious, inhabits different environments?
P. aeroginosa
