MISC ANTIBIOTICS

Question 1

name this misc antibiotics

binds to the same site on the 50S subunit as macrolides

Answer 1

clindamycin

Question 2

name this misc antibiotics

a nitroimidazole antiprotozoal drug with potent activity against anaerobes

Answer 2

metronidazole

Question 3

name this misc antibiotics

inhibits bacterial protein synthesis by binding to the p-site on the 50S ribosomal subunit

• bacteriostatic for staph and enterococci
• bactericidal for strep

Answer 3

linezolid

Question 4

name this misc antibiotics

reserved for multi drug resistant organism

Answer 4

quinupristin-dalfopristin

Question 5

name this misc antibiotics

rarely used in the US due to better alternatives that are safe and less prone to resistance

Answer 5

chloramphenicol

Question 6

this antibiotic is good spectrum against MRSA

clinical use:
toxin producing S. pyogenes and S. aureus inhibiting production of toxins
-toxic shock syndrome
-toxin production can lead to

BB warning:
C. diff associated colitis

Answer 6

clindamycin

Question 7

what is the MOA for metronidazole?

*interactions?

Answer 7

selectively absorbed into anaerobic bacteria and protozoa

reduction processes

toxic compounds accumulate in cell

bactericidal

*alcohol causes disulfiram like rxn if consumed within 3 days after therapy

Question 8

this is what med?

good spectrum

• gram positives, strep, staph (MRSA)
• enterococci

clinical use:
SSTI, pneumonia (MRSA), VREs

drug interaction:
non selective inhibitor of MAO

Answer 8

linezolid

Question 9

what is this med?

spectrum-E. faecium like VRE

for multidrug resistant organisms

ADRs
phlebitis, myalgia, arthralgias
requires central line administration

Answer 9

quinupristin-dalfopiristin

Question 10

what is this med?

clinical use: life threatening infections

ADRs:
gray baby syndrome
life threatening infections

Answer 10

chloramphenicol