BETA LACTAMS

Question 1

these are what preg category?

Answer 1

category B

Question 2

the bacterial cell wall is composed of what?

Answer 2

complex, cross linked polymer of polysaccharides and peptides (peptidoglycan)

Question 3

beta lactams bind too?

Answer 3

transpeptidase halting peptidoglycan synthesis

Question 4

what are the natural penicillins?

Answer 4

PCN G, PCN V

Question 5

PCN G is given what route?

Answer 5

IV/IM

Question 6

PCN V is given what route?

Answer 6

oral

Question 7

natural penicillins are ineffective against?

Answer 7

S. aureus

Question 8

this is given IM only, one shot that stays in system for weeks?

used for syphilis, upper respiratory infections, pharyngitis?

Answer 8

penicillin G benzathine

Question 9

this is given IV or IM

leading to more severe infections (neurosyphilis, endocarditis)

Answer 9

penicillin G aqueous crystalline

Question 10

this is given oral only to treat pharyngitis, erysipelas, etc…

Answer 10

penicillin V

Question 11

these are the good spectrum for which penicillin?

streptococci, treponema pallidum, faecalis, diphtheriase, clostridium, pasturella multicida

Answer 11

good spectrum

Question 12

what are the main antistapholococcal penicillins?

Answer 12

nafcillin, oxacillin, dicloxacillin

Question 13

name this antistapholococcal penicillin?

IV only
used for serious infection due to MSSA

Answer 13

nafcillin

Question 14

name this antistapholococcal penicillin?

IV/IM
same as nafcillin

Answer 14

oxacillin

Question 15

name this antistapholococcal penicillin?

oral
used for mild to moderate infections (impetigo, SSTI)

Answer 15

dicloxacillin

Question 16

these are the good spectrum for which penicillin?

MSSA

Answer 16

antistapholococcal penicillin

Question 17

which are the important aminopenicillins?

Answer 17

ampicillin

amoxicillin

Question 18

name this amino penicillin?

IV-moderate to serious infections (endocarditis, meningitis, bacteremia)

Answer 18

ampicillin

Question 19

name this amino penicillin?

IV-mild to moderate infections like sinusitis, otitis media, tonsillitis?

Answer 19

amoxicillin

Question 20

these are the good spectrum for which penicillin?

strep
enterococci
listeria monocytogenes
n meningitides
p. multocida
actinomyces

Answer 20

aminopenicllins