BETA LACTAMS Flashcards
these are what preg category?
category B
the bacterial cell wall is composed of what?
complex, cross linked polymer of polysaccharides and peptides (peptidoglycan)
beta lactams bind too?
transpeptidase halting peptidoglycan synthesis
what are the natural penicillins?
PCN G, PCN V
PCN G is given what route?
IV/IM
PCN V is given what route?
oral
natural penicillins are ineffective against?
S. aureus
this is given IM only, one shot that stays in system for weeks?
used for syphilis, upper respiratory infections, pharyngitis?
penicillin G benzathine
this is given IV or IM
leading to more severe infections (neurosyphilis, endocarditis)
penicillin G aqueous crystalline
this is given oral only to treat pharyngitis, erysipelas, etc…
penicillin V
these are the good spectrum for which penicillin?
streptococci, treponema pallidum, faecalis, diphtheriase, clostridium, pasturella multicida
good spectrum
what are the main antistapholococcal penicillins?
nafcillin, oxacillin, dicloxacillin
name this antistapholococcal penicillin?
IV only
used for serious infection due to MSSA
nafcillin
name this antistapholococcal penicillin?
IV/IM
same as nafcillin
oxacillin
name this antistapholococcal penicillin?
oral
used for mild to moderate infections (impetigo, SSTI)
dicloxacillin
these are the good spectrum for which penicillin?
MSSA
antistapholococcal penicillin
which are the important aminopenicillins?
ampicillin
amoxicillin
name this amino penicillin?
IV-moderate to serious infections (endocarditis, meningitis, bacteremia)
ampicillin
name this amino penicillin?
IV-mild to moderate infections like sinusitis, otitis media, tonsillitis?
amoxicillin
these are the good spectrum for which penicillin?
strep enterococci listeria monocytogenes n meningitides p. multocida actinomyces
aminopenicllins
