DIURETICS PHARMACOLOGY III Flashcards
1
Q
carbonic anhydrase inhibitors MOAs?
A
inhibition of CA decerases sodium bicarb reabsorption in the proximal tubule this water follows causing potential metabolic acidosis decreasing the diuresis effectiveness
2
Q
how do we treat metabolic alkolosis of loop diuretics?
A
CA inhibitors
3
Q
indications of CA inhibitors?
A
acute altitude sickness
4
Q
ADH antagonists?
A
Conivaptan-Vaprisol
Tolvaptan-Samsca
5
Q
ADH antagonists MOA?
A
inhibit ADH antagonists in the collecting ducts of the nephron to promote free water excretion
6
Q
ADH antagonist clinical uses?
A
syndrome of inappropriate ADH secretion
hypervolemic hyponatremia seen in heart failure
