MAJOR DEPRESSIVE DISORDER HIGH YIELD

Question 1

depressed mood for at least 2 weeks

disturbances in sleep and appetite, cognition, energy

thoughts of guilt, worthlessness

Answer 1

major depressive disorder (MDD)

Question 2

name this model

related to a deficiency in the amount of cortical and limbic serotonin, NE and dopamine
-drugs to treat depression will mostly work on these

Answer 2

monamine model

Question 3

how unsuccessful are antidepressants?

Answer 3

1/3 of patients

Question 4

what are phases for MDD treatment?

Answer 4

acute phase
continuation phase
maintenance phase

Question 5

name this phase?

6-12 weeks
goals=full remission of symptoms and return to baseline

Answer 5

acute phase

Question 6

name this phase?

4-9 months
goals=prevent relapse

Answer 6

continuation phase

Question 7

name this phase?

1-3 yrs
goal=prevent further occurrences of depression

Answer 7

maintenance phase

Question 8

treatment choices for depression?

Answer 8

pharmacotherapy
electroconvulsive therapy
psychotherapy

Question 9

first antidepressants may be beneficial in only what percent of cases?

Answer 9

50-60%

Question 10

treatment goals?

Answer 10

reduce symptoms of depression
return to euthymia
prevent relapse
prevent suicide
facilitate patient return to normal

Question 11

what are the pharmacotherapy treatments for MDD?

Answer 11

SSRI
SNRI
MAO-I
TCA
Misc Anti