FLUOROQUINOLONES Flashcards
1
Q
what is this drug?
synthetic fluorinated analogs of nalidixic acid
- covers a wide range of gram positive and negative bugs
- bactericidal
- wide range of use of these agents has led to increasing bacterial resistance
A
fluoroquinolones
2
Q
resistance to?
A
cross resistance to all members of the class when resistant to one
3
Q
examples of meds used for respiratory-pneumonia?
A
only levofloxacin and moxifloxacin; NOT ciprofloxacin
4
Q
what is the BB warning?
A
tendon rupture/tendonitis
5
Q
major rule of quinolone use in pediatrics?
A
FQs are not routinely used in patients under 18 y/o
6
Q
what are the drug interactions of quinolones?
A
divalent/trivalent cations reduce absorption of quinolones
