TETRACYCLINES Flashcards
1
Q
what are the examples?
bacteriostatic or bactericidal?
A
doxycycline
minocycline
tetracycline
tigecycline
bacteriostatic
2
Q
what is the MOA?
A
30S ribosomal subunit
3
Q
distribution?
A
bones
dentine
enamel
unerupted teeth
4
Q
tetracycline, doxycycline, minocycline has spectrum against?
A
staph (MRSA), strep atypicals rickettsia spirochetes plasmodium species
5
Q
tigecycline and eravacycline has spectrum against?
A
atypical enterococci (VRE) staph (MRSA) strep GNRs
except pseudomas
6
Q
used for most importantly?
A
life threatening infections involving resistant bacteria
7
Q
ADRs and preg? *developmentally
A
avoid in preg (Cat D) and children under 8