PHARMACOKINETICS AND DRUG ADM PART B

Question 1

the amount of drug eliminated per unit time is proportional to the plasma concentration of the drug
-20% of the drug eliminated per hour

Answer 1

first order elimination (concentration-dependent)

Question 2

elimination rate is fixed to an amount of drug per unit time
i.e. 20 mg of drug eliminated per hour

Answer 2

zero order elimination

Question 3

this describes enzymatic reactions where a maximum rate of reaction is reached when drug concentration achieves 100% enzyme saturation

Answer 3

Michaelis-menten kinetics

Question 4

single large dose of a drug that is used to raise the plasma concentration to a therapeutic level more quickly than would occur through repeated smaller doses

Answer 4

loading dose