HYPNOTICS Flashcards
1
Q
aka?
*for insomnia
A
nonbenzodiazepine receptor agonists
2
Q
what receptor is activated?
effect?
NBBRAs cons?
A
BZ2 receptor
enhanced activity of GABA with hypnosedative and amnesic effects (induces CNS depression)
sleep walking and activities
3
Q
Black Box warning – complex sleep behavior
A
Zolipdem
4
Q
these put you to sleep?
A
Zolipdem
Zalepion
Eszopiclone
5
Q
misc agents for insomnia?
A
ramelteon
suvorenxant
6
Q
name this misc agents for insomnia?
melatonin receptor agonist
-no effect on GABA or BZD receptor so no risk of dependence
A
Ramelteon
7
Q
name this misc agents for insomnia?
Orexin*** receptor antagonist
- Contraindicated in narcolepsy
- -since the orexin receptor has been indicated in narcolepsy
–Adverse Effects = sleep paralysis, cataplexy symptoms
A
Suvorexant
8
Q
what are Orexin?
A
wake promoting neuropeptides
