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PHARMA I > ANTIBIOTICS II > Flashcards

ANTIBIOTICS II Flashcards

1
Q

glycopeptides?

main traits?

dosing method used?

A

vancomycin

D-ala-D-ala
bactericidal
renal adjustment

traditional method, trough

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2
Q

vancomycin 10-15 mg/l dosage?

A

SSTI
ulcers
UTI

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3
Q

vancomycin 15-20 mg/l dosage?

A

more serious infection, pneumonia, meningitis, endocarditis

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4
Q

vancomycin ADRs/preg?

A

infusion related
nephrotoxicity
oxotoxcity

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5
Q

aminoglycosides for acute bacterial skin and skin structure infections caused by susceptible gram positive organism?

MOA is same as vancomycin

A

dalbavancin

oritavancin

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6
Q

MOA of daptomycin?

inactivated?

A
  • binds to calcium allowing it to bind to the bacterial membranes
  • also bactericidal

*pulmonary surfactant

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7
Q

major consideration of daptomycin?

good spectrum?

A

not for respiratory infections

MSSA
MRSA
strep

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8
Q

daptomycin uses?

A

complicated SSTI
S. aureus bacteremia
joint infections
endocarditis

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9
Q

ADR/Preg MSK in patients who take daptomycin?

A

check creatine kinase
myopathy
rhabdomyolysis

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PHARMA I (138 decks)

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