Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ABSN > TB pharm - Exam 1B > Flashcards

TB pharm - Exam 1B Flashcards

1
Q

what class is Isoniazid (INH)

A

Antitubercular drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Isoniazid MOA

A

Disrupts cell wall synthesis essential functions of mycobacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Isoniazid indication

A

First line TB med

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Isoniazid SE

A

Peripheral neuropathy, hepatotoxicity, optic neuritis/visual disturbance, hyperglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Isoniazid nursing considerations

A

BBW: increased risk of hepatitis (often given w/ vit B6)

Avoid antacids

When given with rifampin, can increase CNS & hepatotoxicity

If given w/ phenytoin, can increase phenytoin effect

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Rifampin MOA

A

Inhibits protein synthesis via attacking the hydrocarbon ring structure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what class is Rifampin

A

Antitubercular drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Rifampin indications

A

Mycobacterial infections

meningitis, HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rifampin SE

A

Hepatitis, hematologic disorders, red/brown discoloration of the urine & other body fluids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Rifampin nursing considerations

A

Lots of drug-drug interaction so consult HCP & pharm before taking (may need to increase dose of the other meds)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what class is Ethambutol

A

Antitubercular drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ethambutol MOA

A

Diffusing into the mycobacteria and suppresses RNA synthesis, which inhibits protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Ethambutol indication

A

First line bacteriostatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ethambutol SE

A

Retrobulbar neuritis
Blindness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ethambutol nursing consideration

A

Usually given in combo with INH and rifampin

Not for children <13 yrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what class is Pyrazinamide

A

Antitubercular drug

16
Q

Pyrazinamide MOA

A

Unknown -> thought to inhibit lipid and nucleic acid synthesis

17
Q

Pyrazinamide indications

A

Bacteriostatic or bactericidal depending on drug concentration

18
Q

Pyrazinamide SE

A

Hepatotoxicity
Hyperuricemia

19
Q

Pyrazinamide nursing considerations

A

Contraindicated in severe hepatic disease or acute gout

Not for pregnant people in USA

20
Q

what class is Streptomycin

A

Antitubercular drug

21
Q

Streptomycin MOA

A

Aminoglycoside – interfering with normal protein synthesis causing production of faulty proteins within the bacteria

22
Q

Streptomycin indication

A

TB

23
Q

Streptomycin SE

A

Ototoxicity
Nephrotoxicity
Blood dyscrasias

24
Q

Streptomycin nursing considerations

A

can increase bleeding so careful with people on anticoags

given IM

ABSN (90 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions