Immunity (325E1) Flashcards
3 processes of inflammation
1) destroy invading and harmful agents
2) limit the spread of harmful agents
3) prepare damaged tissue for repair
when is inflammation a problem
when left unchecked
what are the 5 signs of localized inflammation
redness, swelling, heat, pain, loss of function
exogenous causes of inflammation
“we did something to our body” falls, burns, surgery, trauma
endogenous causes of inflammation
(lack of O2) tissue ischemia
acute inflammation
<2 weeks
chronic inflammation
> 2 weeks
what type of mechanism is inflammation
a protective mechanism that begins the healing process
events of inflammation
1) tissue injury or bacterial antigens (stimulates response)
2) vasodilation and increased vascular permeabiltiy
3) leukocyte recruitment & emigration (chemotaxis)
4) phagocytosis of antigens and debris
chemotaxis
process by which neutrophils are attracted to inflamed tissue
exudate: serous
watery, low protein, mild inflammation good kind
exudate: serosanguineous
pink tinged fluid, small amounts of RBC usually normal in post opt events
exudate: purulent (can be called fibrinous)
severe inflammation with bacterial infection, neutrophils, protein, and debris (abscesses may require draining) ** more concerning, thick & sticky**
exudate: hemorrhagic
lots of RBCs, most severe inflammation can be confused w/ bleeding, consider there might be bleeding else where and there is a problem
cytokines are responsible for what
systemic manifestations of inflammation
what are the signs of systemic inflammation
fever
-increased neutrophils (wbc)
-lethargy
-muscle catabolism
find source of infection