Chapter 3: Immunologic Diseases and Conditions: Prognosis

Question 1

What is the prognosis of Acquired immunodeficiency Syndrome (AIDS)

Answer 1

treatment include use of HAART, use of antibiotics, and care by a physician experienced with HIV care

Question 2

What is the prognosis of Common Variable immunodeficiency (Acquired Hypogammaglobulinemia)

Answer 2

use of immunoglobulins improved prognosis. Chronic lung disease or malignancies often succumb

Question 3

What is the prognosis of Selective Immunoglobulin A Deficiency

Answer 3

prognosis is generally good; some children show spontaneous resolution of condition

Question 4

What is the prognosis of X-linked Agammaglobulinemia

Answer 4

cannot be cured, regular infusions of immune globulin may provide the patient with an almost normal lifestyle

Question 5

What is the prognosis of Severe Combined Immunodeficiency

Answer 5

unless gene defect corrected, children die of overwhelming infection before age of 1 year

Question 6

What is the prognosis of DiGeorge’s Anomaly (Thymic Hypoplasia or Aplasia)

Answer 6

complete is usually fatal within first year of life because of cardiac dysfunction

Question 7

What is the prognosis of Chronic Mucocutaneous Candidiasis

Answer 7

death due to CMC is unusual since infections are usually localized; antifungals has good results, relapse after cessation of agents

Question 8

What is the prognosis of Wiskott-Aldrich Syndrome

Answer 8

long term survival is good for patients who receive BMT before age of 5 years

Question 9

What is the prognosis of Autoimmune Hemolytic Anemia

Answer 9

infection or drug use will usually abate after the infection resolves or the drug is discontinued; other causes is often chronic and poorly responsive to therapy

Question 10

What is the prognosis of Pernicous Anemia

Answer 10

early detection and treatment with B12 maintains normal life

Question 11

What is the prognosis of Idiopathic Thrombocytopenia Purpura

Answer 11

spontaneous remission of the disease, many times occurring within 2 to 8 weeks of diagnosis; 1% of patients die if severe

Question 12

What is the prognosis of Immune Neutropenia

Answer 12

usually resolves spontaneously; follows benign cours, with appropriate treatment

Question 13

What is the prognosis of Goodpasture’s Syndrome

Answer 13

self-limited and those who survive for a year after and maintain intact renal function usually do well

Question 14

What is the prognosis of Systemic Lupus Erythematosus

Answer 14

improve each decade with development of more accurate monitoring tests and treatment; increase risk for developing cancer

Question 15

What is the prognosis of Scleroderma (Systemic Sclerosis)

Answer 15

depends on which organs are affected and the severity of the organs involved

Question 16

What is the prognosis of Sjorgren’s Syndrome

Answer 16

depends on complications and/or antimalarial nedications such as hydroxychloroquine are used to lessen immune inflammation

Question 17

What is the prognosis of Rheumatoid Arthritis

Answer 17

depends on adequacy of treatment, which must involve a close interaction between patient and physician

Question 18

What is the prognosis of Juvenile Rheumatoid Arthritis

Answer 18

proper therapy, children with all forms of arthritis will usually improve over time

Question 19

What is the prognosis of Ankylosing Spondylitis

Answer 19

variable with periods of remission and episodes of exaccerbation; male gender and early onset bad

Question 20

What is the prognosis of Polymyositis

Answer 20

recover well from effects, especially with early medical treatment of the disease and its flares

Question 21

What is the prognosis of Multiple Sclerosis

Answer 21

no cure is known and duration is variable; females, early age onset, relapsing and in patients with impairment of sensory pathways as initial symptom

Question 22

What is the prognosis of Myasthenia Gravis

Answer 22

unexplained spontaneous remissions can occur; however, the disease is usually lifelong condition characterized by remissions and exacerbations

Question 23

What is the prognosis of Small Vessel Vasculitis

Answer 23

outlook for patients with small vessel vasculitis is generally very good. Tends to readily respond to treatment

Question 24

What is the prognosis of Systemic Necrotizing Vasculitis

Answer 24

is guarded until the condition is controlled with medications to suppress inflammation and immune activity