Skin OTC - Acne

Question 1

Define Acne.

Answer 1

Chronic inflammatory disorder of sebaceous follicles of face, chest and back

Question 2

What can cause Acne?

Answer 2

Increased sebum production
Follicular hyperkeratosis
Propionbacterium acnes
Inflammation
Excessive hormone response
Occluded pores

Drug induced: Oral contraceptives, phenytoin, lithium

Question 3

What are the treatment options for Acne?

Answer 3

Benzoyl peroxide - topical oxidising agent that’s bactericidal for P.acnes and has anti-comedogenic activity (Acnecide, Quinoderm) 5-10%, Keratolytic
Causes dryness, irritation and peeling
Sunlight beneficial for acne but avoid strong sun.
Unlikely to see immediately response, usually takes up to 4 weeks to work - if no response within 2-3 months = refer
Counsel on application.

Question 4

What is the referral symptoms of acne? (2)

Answer 4

Moderate/severe acne
Tx failure after 2-3 months.

Question 5

Give e.g. of POM tx for Acne.

Answer 5

Azelaic acid
Tetracyclines
Topical ABx
Diane TTR
Nicotinamide (GSL - Freederm)
Isotretinoin (Roaccutane/Tretinoin)
Can take weeks/months for effect.