POM-P Switches - Otrivine

Question 1

What is the indication of Otrivine? (1)

Answer 1

Dual relief Nasal Spray (P): 0.5mg xylometazoline HCl + 0.6mg/ml ipratropium bromide.
- Symptomatic relief of nasal congestion and rhinorrhoea in common colds.

Question 2

What is the license age for Otrivine? (1)

Answer 2

18+

Question 3

What is the dose of Otrivine? (1)

Answer 3

1 spray in each nostril up to max TDS (at least 6 hrs between each dose)

Question 4

What is the max treatment duration of Otrivine? (1)

Answer 4

7 days - high risk of rebound congestion (stop sooner if improvement)

Question 5

What are the common s/e of Otrivine? (5)

Answer 5

Visual disturbances
Dizziness
Fatigue
Epistaxis (nose bleeds)
Nasal dryness

Question 6

What are the contraindications for Otrivine? (3)

Answer 6

Hypersensitive to ingredients
After nasal surgery
Glaucoma

Question 7

Which patients should you avoid giving Otrivine? (2)

Answer 7

Pregnancy
Breastfeeding

Question 8

What are the cautions for using Otrivine? (11)

Answer 8

Hypertension
Px with long QT syndrome (increased risk of serious ventricular arrhythmias)
Hyperthyroidism
Diabetes
Prostate Hypertrophy
Bladder Stenosis
Cystic Fibrosis
MAOI tx or received them in last 2 weeks.
Tri- or teracyclic antidepressants or received them in last 2 weeks.
B2-agonists
Angle closure glaucoma.