Commonly Rx Drugs - Nitrofurantoin

Question 1

What is Nitrofurantoin?

Answer 1

ABx

Question 2

What is the indication of Nitrofurantoin?

Answer 2

1st line for UTI

Question 3

Explain the implications of using Nitrofurantoin with renal impairment. (3)

Answer 3

Antibacterial effect depends on renal secretion of the drug into the urinary tract.
Avoid if eGFR = < 45ml/min/1.73m2.
Caution with eGFR between 30-44ml/min/1.73m2.