Commony Rx Drugs - Clozapine Flashcards
1
Q
What is Clozapine?
A
Antipsychotic
2
Q
When would Clozapine be used as tx? (1)
A
Schizophrenia (unresponsive to or intolerant of conventional antipsychotic drugs.)
3
Q
What are the common s/e of Clozapine? (3)
A
Agranulocytosis (specialist monitoring services)
Intestinal obstruction
Constipation
4
Q
What are the main drug interactions with Clozapine?
A
Drugs that causes agranulocytosis and constipation.
5
Q
When would it be appropriate to make dose adjustments?
A
Stopped smoking or started smoking during tx.
6
Q
What measures should be carried out if Clozapine dose has been missed > 48 hrs?
A
Re-titrate dose.
7
Q
What main s/e should px report when taking Clozapine? (1)
A
Constipation
