6 - Gynae - Disorders of the Vulva and Vagina - Premalignant Disease of the Vulva: VIN Flashcards
1
Q
what is VIN
2 types based on ?
what are 2 types?
A
presence of atypical cells in vulval epithelium - histopathology
usual type VIN
Differentiated Type VIN
2
Q
usual type VIN - nearly all of VIN - commonest age group? ass w 4 things?
it may multifocal, appearance varies: colour? morphology? erosions, ? , warty or ?
this type ass w warty/basaloid ?
A
35-55y HPV esp16, CIN, SMx, immsupp red/white/pigmented plaques/patches/papules, nodules, hyperkeratosis SCC
3
Q
Differentiated Type VIN - rarer - ass w lichen ?
seen in ? women
lesion usually ? in form of plaque/ulcer, linked to ? SCCs of the vulva
risk of progression to cancer ? than usual type
A
sclerosus older unifocal ulcer/plaque keratinising higher
4
Q
2 Sx common with VIN
2 topical trts?
what is gold standard tx? this also allows confirming ? and excludes ??
15% at ? have unrecognised ? disease, so must take ? if not operating
A
pruritis/pain emollients/mild topical steroids surgical excision histo invasive disease excision invasive biopsies
