3 - Derm - Benign and Malignant Melanocytic lesions - Melanoma 1

Question 1

incidence of melanoma
slightly more common in who
% of skin cancer deaths?

Answer 1

~10/10000
women
80

Question 2

RFs for melanoma

Answer 2

UV exposure
fair skin
FHx
immunosuppression
large congenital naevi
old age
multiple atypical naevi

Question 3

Clinical features - Glasgow 7 point checklist - maj points

Answer 3

major point/3 minors = suspicion

maj -
1 - irregular shape/asymmetry
2 - changing or irregular colour
3 - changing size

Question 4

Clinical features - Glasgow 7 point checklist - min points

Answer 4

min-
4 - oozing/crusting/bleeding
5- sensation change, itching
6- inflammation
7- largest diameter >7mm

Question 5

types of melanoma - 4 overall types

Answer 5

Acral
nodular
superficial spreading
lentigo/lento maligna

Question 6

Lento maligna - what happens, where? begins as? duration?

Answer 6

malignant proliferation of melanocytes confined to epidermis
at sun exposed sites
begins as large freckle
long history

Question 7

Lento maligna - peak age? ass w? not ass w?

Answer 7

60-80
ass w UV exp
not ass w pre existing naevi

Question 8

Lento maigna - features - 4

Answer 8

large (>6mm)
irregular border
variable colour
smooth surface

Question 9

Lento maligna - mgmt

Answer 9

surgical excision with 5mm margin

Question 10

Lentigo maligna melanoma - dif from lento?

Answer 10

when malignant cells invade dermis - 3-10%

Question 11

Lentigo maligna melanoma - features

Answer 11

thickening of lesion - can become nodular
variability in colours (blue, black)
2ndary features - ulceration bleeding, itching, stinging