2 - Derm - Skin + Systemic disease - Thyroid disease, SLE, Erythema nodosum

Question 1

Hyperthyroidism

-5 skin changes

Answer 1

pretibial myxoedema
fine thin scalp hair
pruritis
urticaria
nails - acropachy, clubbing, oncholysis

Question 2

Pretibial myxoedema - most commonly from? features?

Answer 2

Graves disease

mucin deposition - swollen, lumpy shins, pink or purple discolouration with prominent hair follicles, waxy indurated nodules or plaques, can be painful or itchy

Question 3

Hypothyroidism - 4 things

Answer 3

harsh, brittle hair coming out in clumps
carotenaemia
dry skin
myxoedema - puffy eyelids and hands

Question 4

SLE - skin affected in what kind of SLE

- more common in who?

Answer 4

mainly seen in acute SLE

more common in women

Question 5

SLE - describe skin change? when occurs? does it stay?

Answer 5

malar butterfly rash,

transient, often response to sun, non-scarring

Question 6

SLE - associated w? tests?

Answer 6

ass w mouth ulcers, urticaria, hair thinning

anti-nuclear antibody (ANA), anti-dsDNA

Question 7

Erythema nodosum

• describe
• where
• common associations

Answer 7

• tender erythematous, bruise like lesions usually on lower leg
• ass w malaise, fever, joint pain

Question 8

Erythema nodosum

-age? gender prevalence? disease course?

Answer 8

at age 15-30
3x more in women
usually resolves after 2-4 weeks

Question 9

Erythema nodosum

• triggers
• mgmt

Answer 9

infection - strep, TB
drugs - OCP
systemic - IBD, saroidosis

mgmgt = NSAIDs