3 - Derm - Benign and Malignant Melanocytic lesions - Melanoma 2 Flashcards
superficial spreading melanoma (SSM) - how common? how does it grow?
most common - ~70%
radial growth within epidermis
some are invasive and enter dermis
SSM - ass w
increased age
UV exp
high numbers of typical/atypical naevi (~25% from pre-existing naevi)
SSM - locations M + F
m - commonly trunk
f - commonly legs
SSM clinical features
large size >6mm
irregular border
variable colour
smooth surface, then thicker, possibly dry and warty
SSM - indicators of invasive melanoma
thickening
increase variability of colours
2ndary features - ulceration, bleeding, itching, stinging
Nodular - how aggressive? less ass w what? commonly arises from?
most aggressive
less ass w UV
most commonly from normal skin/melanoma, occasionally from naevus
Nodular - ass w? prognosis is? DDx?
ass w high typ/nontyp naevi numbers + prev/current melanoma
poor prog
confused with pyogenic granuloma
Nodular - clinical features
> 6mm dome shaped firm lump
variable pigmentation - skin/black/no pigment
surface - smooth/rough/crusted/warty
commonly - ulceration, bleeding itching, stinging
Acral melanoma - where? how common? common in?
arises on palms soles or under nail
rare - more in darker skinned
Acral - not related to? disease course?
Not related to UV exposure
initial in-situ phase - may become rapidly invasive
