VIRAL HEPATITIS Flashcards
HEPATITIS VIRIDAE
Viral Hepatitis – _____ of the ________
Infection
liver hepatocytes
____ known types of Hepatitis Virus
_____ RNA Viruses (________________ )
_____ DNA Viruses (________________ )
6
5; HAV, HCV, HDV, HEV, & HGV
1; HBV
HEPATITIS VIRIDAE
HAV & HEV are transmitted via __________ route
All others are transmitted via ___________
fecal-oral
blood to blood contact
HEPATITIS VIRIDAE
_______________ are transmitted via fecal-oral route
All others are transmitted via blood to blood contact
HAV & HEV
HEPATITIS VIRIDAE
It could be a sudden illness with a ___________ course followed by __________ (_____ viral hepatitis)
It could have a prolonged course of _______ or __________ ( _______ viral hepatitis)
mild to severe
complete resolution; acute
active disease or silent asymptomatic infection; chronic
HEPATITIS A VIRUS
Naked or Enveloped
__________ capsid
_____ stranded RNA
Family – ______viridae
Naked
icosahedral
+ss
Picorna
HEPATITIS A VIRUS
A stands for _____ (_____)
______ cases reported each year
Anal
Anus
25,000
HEPATITIS A VIRUS
(Young or Old?) (children or adults?) are mostly frequently affected
_________ tests can help establish diagnosis
Young children; Serologic
HEPATITIS A VIRUS
HAV capsid is antigenic
Antibodies produced last few years & is protective
A new vaccine is available
T/F
T
F
T
HAV capsid is antigenic
Antibodies produced last indefinitely & is protective
A new vaccine is available
HEPATITIS B VIRUS
The intact virus called “____________ ”
Naked or Enveloped?
________ capsid studded with _______
Dane particle
Enveloped
Icosahedral
protein spikes
HEPATITIS B VIRUS
_______ stranded (DNA or RNA?) core with associated ————- enzyme
Belongs to the _______________ family
Double
DNA
DNA polymerase
Hepadnavirus
HEPATITIS B VIRUS
Many antigenic sites:
– Hepatitis B _____ antigen (_____)
– Hepatitis B ______ antigen (_____)
– Hepatitis B ___ antigen (______)
surface; HBsAg
core; HBcAg
E; HBeAg
HEPATITIS B VIRUS
Virus present in human _____
HBV is (a bit or very?) contagious
Causes ______________ hepatitis
fluid
Very
both acute & chronic
HEPATITIS B VIRUS
Serologic tests also important in diagnosis
–__________________ – New infection
–____________ – old infection
–_______ – High Infectivity
–__________ – Low Infectivity
IgM anti-HBcAg
IgG anti-HBcAg
HBeAg
Anti-HBeAg
HEPATITIS B VIRUS
Serologic tests also important in diagnosis
– IgM anti-HBcAg –_____ infection
– IgG anti-HBcAg –_______ infection
– HBeAg – _____ Infectivity
– Anti-HBeAg –____ Infectivity
New
old
High
Low
