Cutaneous mycosis Flashcards
Morbidity and Mortality of cutaneous mycoses
Infections are (common or rare?)
Exact prevalence (known or unknown?)
More common in (children or adult?)
Common
Unknown
Children
Morbidity and Mortality of cutaneous mycoses
Most infections are (serious or not serious?)
Immuno________ individuals
(Typical or Atypical?) , (locally or systemically?) aggressive lesions
Not serious
suppressed
Atypical, locally
DERMATOPHYTOSES
Three genera- _______,_______,_______
Trichophyton, Epidermophyton, Microsporum
Anthropophilic-reside on the ________
Zoophilic-reside on the ___________
Geophilic-reside in _____
human skin
skin of domestic and farm animals
Soil
DERMATOPHYTOSES
Transmission from humans or animals is by _______
infected skin scales
DERMATOPHYTOSES
Pathology
Dermatophytes use ______ as a source of nutrition
keratin
DERMATOPHYTOSES
Pathology
they infect _____,_____,_____
skin, hair, nails
DERMATOPHYTOSES
Pathology
All 3 organisms infect ________
attack skin
Microsporum does not infect _____
nails
Epidermophyton does not infect ________
hair
Dermatophytes invade underlying non- keratinized tissues
T/F
F
they do not invade underlying non- keratinized tissues
Zoophilic dermatophytes?
Microsporum
Trichophyton
CLINICAL SIGNIFICANCE
DERMATOPHYTOSES
Characterized by _____ ,________ that can become _______ and ____
itching,scaling skin patches
inflamed and weeping
DERMATOPHYTOSES Infection in different sites may be due to different organisms and is given different names
T/F
F
but is given one name
DERMATOPHYTOSES
Transmission Contact with:
–_______
–______
Arthrospores
Conidia
DERMATOPHYTOSES
Transmission Contact with:
– Arthrospores
• ( Sexual or Asexual?) spores formed in the _______ of the ______ stage
Asexual
hyphae
parasitic
DERMATOPHYTOSES
Transmission Contact with:
– Conidia
•______________ spores formed in the “ _____ ” _________ stage
Sexual or asexual
free-living
environmental
DERMATOPHYTOSES Transmission
Modes of transmission
– ______ with ____________
– __________ hairs/scales
–_______
– ______
Contact; infected animals/humans
Airborne
Fomites
Soil
tinea _______ - ringworm infection of the scalp (crusty hair)
favosa
tinea ____ - ringworm infection of the body (smooth skin)
corporis
tinea _____ - ringworm infection of the groin (_______)
cruris
jock itch
tinea ______ - ringworm infection of the nails
unguium
tinea _____ - ringworm infection of the beard
barbae
tinea ________ - ringworm infection of the hand
manuum
tinea ______ - ringworm infection of the foot (_______)
pedis
athlete’s foot
tinea ______ - ringworm infection of the heads
capitis
tinea _____ - ringworm infection of the eyebrows
capitis
tinea ____ - ringworm infection of the eyelashes
capitis
tinea ____ - ringworm infection of the scalp
capitis
Diagnosis of dermatophytoses
Collection of samples
Specimens of skin, hair, nails Collected in ______________
folded black paper
Diagnosis
Collection of samples,
Stored up to ___________
12 months
Diagnosis
Collection of samples,
Nails by _______
Skin by _______ with ________
Hair by _______
clippings
scrapping
blunt scalpel
plucking
PITYRIASIS VERSICOLOR (Tinea versicolor)
(Superficial or deep?) (acute or chronic?) infection of _________
Superficial
Chronic
Stratum corneum
PITYRIASIS VERSICOLOR ( ______________ )
Tinea versicolor
PITYRIASIS VERSICOLOR (Tinea versicolor)
Etio: __________ (Pityrosporum orbiculare), a Lipophilic ( yeast or mold?)
Malassezia furfur
Yeast
PITYRIASIS VERSICOLOR (Tinea versicolor)
Manifest as ___________
patches of discoloration of skin,
Diagnosis of P.vesicolor
_______ , can be used to look for _____________ which is typical of pityriasis versicolor.
___________ to confirm the diagnosis.
Wood’s lamp
yellow fluorescence
Skin scrapings
PITYRIASIS vesicolor
Under Direct microscopy has a _________________ appearence
sphagetti and meatball
Dermatophyte infections are not usually limited to the epidermis.
T/F
F
They are
MAJOCCHI’S GRANULOMA
is an uncommon condition in which the dermatophyte invades the ___________ or ________
dermis or subcutaneous tissue.
MAJOCCHI’S GRANULOMA
Can be precipitated by _________ or _________
trauma to skin or occlusion of hair follicles
MAJOCCHI’S GRANULOMA
Common etiological agent is __________
T.rubrum
Lab diagnosis of MAJOCCHI’S GRANULOMA
Skin biopsy
Look for fungal hyphea
*A potassium hydroxide (KOH) preparation, which identifies fungal forms only within the _________, may be (positive or negative?)
stratum corneum
negative
Candidiasis can Present as Skin lesions
T/F
T
Diagnosis
Wood’s lamp examination - detects ___________
Potassium hydroxide microscopy- Detects ______ and ____ in skin scrapings or hair
Fungal cultures- Required to ________
,
Detects fluorescence
hyphae and conidia
identify organism
