Babesiosis

Question 1

Babesiosis is an infectious disease caused by ________ parasites of the genus _______

Answer 1

hemoprotozoan; Babesia

Question 2

Babesiosis

transmitted by infected __________ during blood meal and by transfusion of blood products from asymptomatic donor

Answer 2

ixodes scapularis

Question 3

Babesiosis

Incubation period typically lasts ____________

Answer 3

1 to 6 weeks

Question 4

Clinical features of babesiosis

Often (asymptomatic or symptomatic ?) in young, healthy patients

Self-limited _______-like febrile illness with onset of anorexia, malaise, lethargy
followed in 1 wk by high fever,headache, rigors, myalgias; mild ________, rarely ______ Fever,

Answer 4

asymptomatic

influenza; splenomegaly; hepatomegaly

Question 5

Clinical features of babesiosis

Later ________, _______ anemia, thrombocytopenia, jaundice, acute renal failure, multiorgan failure especially in the _____________,________, or __________

Complications include ________ and ______

Answer 5

hemolysis

hemolytic

splenectomized, elderly, or the immunocompromised

ARDS and DIC

Question 6

Diagnosis of Babesiosis

_______-stained blood smears shows ___________ _____-shaped ______; often in _____ in the form of a ______

Answer 6

Giemsa

intraerythrocytic

ring; trophozoites

tetrads; Maltese cross

Question 7

Treatment of Babesiosis

For mild to moderate disease : combination of __________ and ________

Severe disease: combination of ________ and _________ ± Exchange transfusion

Answer 7

atovaquone and azithromycin.

quinidine and clindamycin

Question 8

Prevention of Babesiosis

Protection from ________

__________________, if a person is bitten

Answer 8

tick bites

Prompt removal of the tick