T-ALL

Question 1

clinical features of T-ALL at presentation

Answer 1

• Marked leukocytosis
• CNS involvement (more common than b cell)
• mediastinal involvement
• often testicular involvement
• commonly have extramedullary involvement of lymph nodes and other organs

Question 2

Drug used for unresponsive or relapsed disease

Answer 2

Nelarabine

Question 3

Markers

Answer 3

CD1a , CD2, CD3, CD4, CD5, CD7, CD8