POEMS syndrome Flashcards

1
Q

Physiology

A

paraneoplastic syndrome from plasma cell disorder

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2
Q

Acronym stands for

A
polyneuropathy
organomegaly
endocrinopathy
m-protein
skin changes
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3
Q

mandatory major criteria for diagnosis

A

1) Polyneuropathy

2) Monoclonal plasma cell disorder

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4
Q

major branch point in management

A

limited vs widespread sclerotic bone lesions

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5
Q

management of patient with 1-2 isolated bone lesions

A

RT

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6
Q

management of patient with more than 2 bone lesions

A

systemic therapy similar to multiple myeloma

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