Lupus anticoagulant

Question 1

Relation to SLE

Answer 1

• most patients with lupus anticoagulant don’t have SLE but SLE patients are more likely to develop a lupus anticoagulant

Question 2

Lupus anticoagulant pathophys

Answer 2

immunoglobulin that binds to phospholipids and proteins associated with the cell membrane.
– pathophys?

Question 3

When do you test for lupus anticoagulant?

Answer 3

Unexplained prolonged PTT

Question 4

Management of lupus anticoagulant

Answer 4

IF they develop VTE, they need indefinite anticoagulation

IF no VTE, just observe