Merkel cell carcinoma

Question 1

Clinical features

Answer 1

Rare, aggressive cutaneous malignancy that predominantly affects older adults with light skin types and has a propensity for local recurrence and regional lymph node metastases.

Question 2

IHC of Merkel cell

Answer 2

neuroendocrine + epithelial

Question 3

First line for stage IV merkel cell carcinoma

Answer 3

avelumab