Non-Hodgkin Lymphoma

Question 1

Which are the indolent NHL types

Answer 1

Follicular lymphoma
Marginal zone lymphoma
Small lymphocytic lymphoma/chronic lymphocytic leukemia
Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia
Cutaneous T-cell lymphoma
Mantle cell lymphoma (indolent and aggressive)

Question 2

Which are the aggressive NHL types

Answer 2

DLBCL
Burkitt lymphoma
Lymphoblastic lymphoma
Mantle cell lymphoma (indolent and aggressive)
Anaplastic large cell
Angioimmunoblastic T-cell
Extranodal

Question 3

what infectious pathogens are associated with lymphoma

Answer 3

HIV
EBV
HTLV-1
H pylori
HHV-8
Hep C
chlamydia
campylobacter
borrelia burgdorferi

Question 4

lymphoma associated with H pylori

Answer 4

mucosa-associated lymphoid tissue (MALT) lymphoma

Question 5

signs/symptoms

Answer 5

b-symptoms – fever, drenching night sweats, unintentional weight loss, anorexia, fatigue.

Question 6

most common NHL subtype

Answer 6

DLBCL

Question 7

most common aggressive NHL

Answer 7

DLBCL

Question 8

Diagnosis of high grade NHL

Answer 8

excisional biopsy, NOT FNA

Question 9

Follicular lymphoma markers

Answer 9

*CD10

Question 10

Mantle cell lymphoma markers

Answer 10

5,19,23

Question 11

hairy cell leukemia markers

Answer 11

19,20

Question 12

marginal zone lymphoma markers

Answer 12

19,20

Question 13

CLL markers

Answer 13

5,19,23

Question 14

Burkitt rearrangement

Answer 14

t(8-14)

Question 15

marginal zone rearrangement

Answer 15

t(11-18)

Question 16

mantle cell lymphoma rearrangement

Answer 16

t(11;14)