pharmacology

Question 1

Lupron

Answer 1

Lupron is a type of gonadotropin-releasing hormone (GnRH) agonist. Prostate cancer.

Question 2

BEP components

Answer 2

bleomycin, etoposide, and cisplatin

Question 3

When mesna is required with cyclophosphamide?

Answer 3

• High dose cyclophosphamide

- Always with ifosfamide

Question 4

neulasta SE’s

Answer 4

• bone pain
• flu like illness

Question 5

How does onpro work?

Answer 5

• delivers neulasta 27 hours after application
• beeps prior to start of drug delivery
• green light flashes during delivery
• red light = error

Question 6

Arixtra generic name

Answer 6

Fondaparinux

Question 7

Nab-paclitaxel mechanism

Answer 7

Taxane combined with albumin (vehicle that enhances delivery of paclitaxel)

Question 8

Regorafenib mechanism

Answer 8

Multikinase – VEGF, RET, Kit, PDGFR, Raf

Question 9

Primary AE to know about with avelumab

Answer 9

Severe infusion reaction (one quarter of patients)

Question 10

What is the only checkpoint inhibitor that requires premedication?

Answer 10

avelumab

Question 11

Drug SE to know with carmustine (BEAM) that can occur a few months after transplant

Answer 11

pneumonitis

Question 12

SE of fedratinib to know

Answer 12

Fatal encephalopathy (Wernicke encephalopathy)