Bone marrow failure Flashcards
1
Q
importance of megakaryocytes in bone marrow
A
Suggests dyspoeisis
2
Q
inherited syndromes associated with bone marrow failure
A
fanconi anemia dyskeratosis congenita GATA2 diamond blackfan anemia severe congenital neutropenia
3
Q
Methods of genetic analysis
A
1) NGS
2) Whole exome sequencing
3) Individual gene sequencing
4
Q
most common cause of bone marrow failure
A
acquired aplastic anemia
5
Q
dyskeratosis congenita pathophys
A
Telemore dysfunction
6
Q
What does term constitutional mean?
A
Heritable
