Glioblastoma multiforme Flashcards
1
Q
Clinical implications of unmethylated MGMT status
A
- leas responsive to temodar
2
Q
basic management
A
concurrent chemoRT with temozolomide with adjuvant temodar
3
Q
PCV regimen
A
Procarbazine, lomustine, and vincristine
4
Q
temozolomide cycle in terms of schedule
A
- daily for 5 days out of a 28 day cycle
5
Q
Only established environmental risk factor for brain and CNS tumors
A
Radiation
*no clear relationship between smoking and CNS tumors
6
Q
Other intervention with an OS benefit
A
Tumor treating fields
7
Q
Mutation associated with positive prognosis in GBM
A
IDH R132 H
