Antiphospholipid antibody syndrome Flashcards
1
Q
CAPS clinical features
A
- widespread thrombotic disease + multiorgan failure
- thromboses involves multiple small blood vessels in various organs rather than a large vessel DVT or CVA
2
Q
APS management during pregnancy
A
IF no history of VTE or arterial clotting, recommend prophylactic aspirin and lovenox for duration of pregnancy and for 6 weeks post-partum
3
Q
Which antiphospholipid carries highest risk of thrombosis in APS?
A
Lupus anticoagulant
4
Q
Titer positivity of anticardiolipin or anti-beta2-glycoprotein antibodies required for diagnosis
A
99th percentile (greater than 40 GPL/MPL for anticardiolipin)
