Mesothelioma Flashcards
1
Q
RF’s
A
- occupational asbestos exposure
- NOT smoking
2
Q
presentation
A
- pleural + peritoneal involvement
- pleural involvement leading to abdominal pain, weight loss, ascites
3
Q
pathologic subtypes of mesothelioma
A
1) epithelial
2) sarcomatoid
3) biphasic
4
Q
most aggressive subtype
A
sarcomatoid
5
Q
management of metastatic sarcomatoid subtype
A
ipi, nivo
6
Q
management of locally advanced mesothelioma (epithelial or biphasic histology)
A
- NAC with cis or carboplatin + pemetrexed –> if favorable response, proceed to surgery –> adjuvant XRT
7
Q
Clinical behavior of malignant mesothelioma
A
- highly aggressive
8
Q
surgery for mesothelioma
A
- pleurectomy/decortication or extrapleural pneumonectomy
9
Q
Chemo regimen for epithelioid mesothelioma
A
cis + pemetrexed +/- bev
10
Q
What are the subtypes of mesothelioma
A
Sarcomatoid
Epitheliod
Biphasic
