This class was created by Brainscape user Ned Jones. Visit their profile to learn more about the creator.

Decks in this class (218)

Acute intermittent porphyria
Diagnosis,
Treatment for acute exacerbations
2  cards
Acute leukemia
Emergencies you need to watch out...,
Blast crises refers to
2  cards
Adrenocortical carcinoma
Most common adrenocortical tumor,
Peak age of incidence for adrenoc...,
Presentation
6  cards
Acute Lymphoblastic Leukemia (B-cell)
Immunophenotypes of all,
Signs symptoms,
Risk stratification of all
109  cards
Acute lymphoblastic leukemia (T-cell ALL)
Definition,
Management in general vs b cell all,
Clinical difference of hyperleuko...
9  cards
Acute Myeloid Leukemia
Medications that are rfs for ther...,
How aml is generally classified,
Presentation
128  cards
Amyloidosis
Cornerstone of treatment,
Standard of care if transplant el...,
Coagulopathy associated with ligh...
12  cards
Anal cancer
Rfs,
How screening for anal cancer is ...,
Most common anal carcinoma histology
39  cards
anemia of chronic disease (anemia of chronic inflammatory disease)
Lab features,
Basic mechanism,
Iron deficiency in anemia of chro...
3  cards
Anemia of CKD/ESRD
Why don t you measure epo,
Why epo has fallen out of favor a...,
Other main mechanism of anemia in...
3  cards
Antiplatelet/anticoagulant therapy
What are the anti thrombins,
How does heparin work,
How does lmwh work
23  cards
Antiphospholipid antibody syndrome
Caps clinical features,
Aps management during pregnancy,
Which antiphospholipid carries hi...
4  cards
APML
How are patients with apl monitor...,
Management of negative pcr after ...,
Management of pcr positive diseas...
27  cards
Appendiceal cancer
How these often are diagnosed,
Management of localized appendice...
2  cards
Aplastic anemia
What is atg,
Promacta generic name,
Pathophys origin of aplastic anemia
17  cards
Arterial thromboembolism
Arterial thromboembolism manifest...
1  cards
Autoimmune hemolytic anemia
Ability to find crossmatch compat...,
Delay in response to steroids,
Antibody positive in aiha
3  cards
Basic science
What is immunophenotyping,
What is the multistep theory of c...,
What is an oncogene
28  cards
Biliary cancer
Rfs for biliary cancers,
Presentation of gallbladder cancer,
How most gallbladder cancers are ...
3  cards
Biopsies
Core vs fna
1  cards
bladder cancer
Preferred first line for metastat...,
Immunotherapy approved for uc gen...,
Histologic types of bladder cance...
45  cards
Bladder cancer 2
What is radical cystectomy,
Accuracy of staging cystoscopy an...,
When bladder preserving approach ...
78  cards
Blood bank
Why are blood components irradiated,
Who needs irradiated blood transf...
2  cards
BMT
What is an ommaya reservoir,
Chemo that may be administered in...,
What does dli stand for
131  cards
Bone marrow biopsy
What is the point of the biopsy s...,
What is the point of the aspirate
2  cards
Bone marrow failure
Importance of megakaryocytes in b...,
Inherited syndromes associated wi...,
Methods of genetic analysis
6  cards
Brain metastasis
Management in general,
Mutational patterns of brain mets...,
Efficacy of chemo vs rt for brain...
5  cards
Breast cancer
Oncotype score,
Interpretation of oncotype score,
Anthracyclines
109  cards
Breast cancer 2
Biopsy type for breast mass,
Her2 scoring system,
Classic features of cancerous les...
167  cards
Burkitt lymphoma
Treatment,
R hyper cvad is,
What is a double hit lymphoma
9  cards
Cancer biology
Biological nature of cancer cells,
What differentiates a benign vs a...
2  cards
Carcinoid tumors
Management of low grade early sta...,
Adjuvant management of low grade ...,
Regimens for carcinoid tumors
4  cards
Cancer of Unknown Primary (CUPS)
General approach
1  cards
CAR-T cell therapy
Basic process,
Medication used for lymphodepletion,
Most important se s to know about
18  cards
Cervical cancer
Fertility preserving option for s...
1  cards
Cholangiocarcinoma
General prognosis,
Symptomatology and physiology of ...,
Difference in lab presentation be...
19  cards
Chronic neutrophilic leukemia
Defining mutation
1  cards
CLL
Risk of relapse with cll,
Preferred first line options for cll,
Cll drug classes
52  cards
Coagulopathy
Differential for prolonged pt inr...,
Differential for normal pt prolon...,
Differential for prolonged pt pro...
6  cards
Coagulation/clotting cascade
First step in hemostasis,
Basic pathophys defect in bernard...,
Basic pathophys defect in glanzma...
14  cards
Clonal hematopoiesis of indeterminate potential (CHIP)
Clinical features,
What to think when you see a clon...,
Classic chip mutations
3  cards
Colony stimulating factors
Granix generic name,
Udenyca,
Neulasta
36  cards
CML
Chromosomes involved in philadelp...,
Name 2 other hematologic malignan...,
3 phases of cml
83  cards
CMML
Lab profile,
Cmml classification,
What are the hypomethylating agents
11  cards
CNS Lymphoma
Cornerstone of treatmetn,
Optimal consolidation therapy,
Consolidation options
13  cards
Colorectal cancer
Relevance of ras in crc,
Microsatelite stability and relat...,
Relevance of microsatelite stabil...
77  cards
Colorectal cancer 2
Surveillance interval for c scope,
Clinical features of palmar plant...,
Tumor marker for crc
109  cards
Cobalamin deficiency
Level indicating deficiency,
Peripheral smear findings
2  cards
Cold agglutinin disease
Treatment,
Direct antiglobulin test result i...,
Lab features
12  cards
Cytogenetics
T 8 21 signifies in general
1  cards
Cutaneous squamous cell carcinoma
Stage iv first line systemic therapy
1  cards
Deep Vein Thrombosis
Severe complication of dvt known as,
Pcd presentation,
Definition of proximal dvt
15  cards
Cord compression
Tumors causing cord compression t...,
Solid tumors causing cord compres...
2  cards
Differentiation syndrome
Cause,
Clinical features,
Cxr with differentiation syndrome
5  cards
DIC
Diagnostic value of schistocytes ...,
Indications for cryo in dic,
Caveat about d dimer and metastat...
19  cards
Cytokine release syndrome
Severe crs management,
When it happens,
Presentation of mild crs
8  cards
Drugs
Xa reversal agent,
Dabigatran reversal agent,
Xa inhibitors
63  cards
Drugs 2
Raloxifene and tamoxifene contrai...,
Egfr inhibitors,
Parp inhibitors
62  cards
Drugs 3
What are the anthracyclines,
What are the camptothecins,
What is folfirinox
16  cards
DLBCL
Staging workup,
Standard treatment for dlbcl,
Management of cns involvement
41  cards
Engraftment syndrome
Clinical features,
Other clinical features,
Pathophysiology
4  cards
Erythrocytosis
Tumors associated with paraneopla...
1  cards
Esophageal cancer
Esophageal scc risk factors,
Esophageal adenocarcinoma rfs,
Percentage of esophageal cancers ...
93  cards
Emergencies
Management of leukostasis in leuk...,
Medical emergency common in apl,
Rfs for differentiation syndrome
5  cards
Factor V Leiden
Pathophys,
Prevalence and penetrance,
Does presence of fvl affect durat...
5  cards
Factor XII deficiency
Lab features,
Inheritance,
Clinical features
3  cards
Essential thrombocythemia
Conditions et can transform into,
High risk definition,
Management
6  cards
Follicular lymphoma
Treatment of grade 3 fl or aggres...,
What is r chop,
Role of maintenance rituximab
49  cards
Gallbladder cancer
General prognosis,
How most are diagnosed,
Rfs for gallbladder cancer
23  cards
Gastroesophageal cancer
Treatment of localized gastroesop...,
General clinical course following...
2  cards
Fanconi anemia
Inheritance,
Overlapping cancer risk,
Presentation
5  cards
Graft versus host disease
Organ systems involved in acute gvhd,
Rf s,
Acute gvhd timing
49  cards
Genetics
Driver mutation,
Transgene,
Ex vivo vs in vivo in gene therapy
16  cards
Gastric cancer
Rfs for gastric cancer,
Protective factors,
Typical stage at presentation
49  cards
G6PD Deficiency
Issue with timing of g6pd
1  cards
Glioblastoma multiforme
Clinical implications of unmethyl...,
Basic management,
Pcv regimen
7  cards
heme 2
Percent saturation,
Percent saturation calculation,
Pod meaning
55  cards
Gastrointestinal stromal tumors (GISTs)
Most common location,
Tissue of origin,
Biochemical signature of gists
17  cards
Hairy cell leukemia
Gene mutation seen in virtually a...,
Presentation of hcl,
Diagnosis
26  cards
Hematopoetic stem cell transplantation supportive care
How to prevent mucositis,
Oral cryotherapy in which cancer ...,
Indication for tpn
35  cards
heme
Lymphoid cells,
Usual exclusion criteria for hct,
Medical conditions that predispos...
60  cards
head and neck cancer
Most common locations of hpv rela...,
Role of egfr in pathogenesis of s...,
Virus associated with nasopharyng...
107  cards
Head and neck cancer 2
What is involved with surveillanc...,
What does crt stand for,
Imaging typically used to assess ...
35  cards
Hemophilia
Inheritance,
Bleeding severity correlates to,
To watch for with bleeding in ext...
33  cards
Hemolytic uremic syndrome
Maha stands fro,
What does maha describe,
What is tma
11  cards
Hyperleukocytosis
Complications of hyperleukocytosis,
Management of apml patient with h...
2  cards
heme 3
Vitamin k deficiency labs,
What is d dimer,
Other reasons for elevated d dimer
62  cards
Hemochromatosis
Pathophys,
Labs,
Presentation
22  cards
Hemolytic anemia
Workup of hemolytic anemia,
Treatment of warm aiha,
Causes of warm aiha
7  cards
HLH
Test characteristics of hemophago...,
Hlh clinical course,
Lab features
10  cards
Immune thrombocytopenic purpura
Itp on peripheral smear,
Clinical course,
Physical exam
9  cards
Heparin induced thrombocytopenia
Scoring system used for hit whats...,
Clinical features of type 2 hit,
Management
23  cards
Hepatocellular carcinoma
Variant of hcc more common in wom...,
Presentation,
Afp specificity other things caus...
46  cards
Hodgkin Lymphoma
Subtypes of classical hodgkin lym...,
Demographics of hl,
How staging generally work
52  cards
Hereditary Cancer Syndromes
Chek2,
Mutation associated with cowden s...,
Genes most commonly implicated in...
44  cards
Hereditary spherocytosis
Management of acute aplastic crisis,
Clinical course,
Transmission
12  cards
Imaging
Why pet ct is variably useful,
If you cant use contrast use,
What is the utility of bone scans
11  cards
Iron Deficiency Anemia
Why iv iron used to be contraindi...,
Time course of response to iv iron,
Efficacy and differences among iv...
44  cards
Hypereosinophilic syndromes (HES)
Diagnostic criteria,
Mortality due to,
Organ systems most commonly affected
5  cards
IHC
Ck7,
Ck20,
Ck17
7  cards
Lab science
How does fish work,
What is the point of fish
2  cards
Immunotherapy
Ae s of checkpoint inhibitors,
Rash in immune checkpoint inhibitors,
When to hold immunotherapy
32  cards
Leukostasis
Slam dunk clinical features,
Treatment options for management ...,
Meds you can use to bring down wb...
7  cards
Important
Toxicity grading
1  cards
Lupus anticoagulant
Relation to sle,
What is a lupus anticoagulant,
When do you test for lupus antico...
4  cards
Iron Overload Syndrome
0  cards
Lymphoma
Molecular basis of richter s tran...,
Term for disease outside of lymph...,
Most common pathogen in hiv assoc...
7  cards
Laryngeal cancer
Management of early stage larynge...,
Locally advanced management
2  cards
Leukemia
Hairy cell leukemia treatment
1  cards
Lytic lesion
Primary concern with lytic lesion,
Fractures occur most commonly in ...,
How to determine fracture risk
4  cards
Logistics
Time it takes for ir or gen surg ...,
Tunneled central venous catheters...
2  cards
MGUS
What is mgus pathophysiologically,
What is a skeletal survey,
Mgus vs smoldering vs multiple my...
9  cards
Lung nodules
Timeframe suggesting nodule is li...,
Features of nodule suggestive of ...
2  cards
mantle cell lymphoma
Clinical course,
General response to treatment,
Therapies
12  cards
Medullary thyroid cancer
Lab that correlates with metastat...,
When ct chest upper abdomen are i...
2  cards
Lymphadenopathy
R supraclavicular lymphadenopathy...,
L supraclavicular lymphadenopathy...
2  cards
Melanoma II
Biomarker that correlates to dise...,
First line for braf mutant in gen...,
What are the mek inhibitors
11  cards
Melanoma
Management of brain mets in melanoma,
Cutaneous vs non cutaneous melanoma,
Stage at which melanoma is typica...
51  cards
Merkel cell carcinoma
Clinical features,
Ihc,
First line for stage iv merkel ce...
3  cards
Marginal zone lymphoma
Classification,
Clinical behavior,
Pathophys
9  cards
Mastocytosis
0  cards
Metastasis
Cancers that metastasize to the b...,
How malignant effusions appear,
What are the typical steps in met...
13  cards
medicine i should know
Abx with mrsa coverage,
Abx with pseudomonal coverage,
Copd diagnosis
28  cards
Myelofibrosis
Etiology of myelofibrosis,
Median survival,
3 most commonly mutated genes in pmf
24  cards
Miscellaneous
Npi number,
Lab profile of vitamin k deficiency,
Normal spleen size
25  cards
Myelodysplastic syndrome
Lab profile,
Indications for treatment of lowe...,
Initial therapy for intermediate ...
53  cards
Myeloproliferative neoplasm
What defines characterizes an mpn,
What are the 7 mpns,
What is jak2s function
8  cards
Meningioma
Rf s
1  cards
Mesothelioma
Rfs,
Presentation,
Pathologic subtypes of mesothelioma
10  cards
Oligodendrogliomas
Prognostic significance of 1p 19q...,
Management following resection
2  cards
Methemoglobinemia
Pathophysiology,
Most commonly implicated meds,
Management
3  cards
Non-Hodgkin Lymphoma
Which are the indolent nhl types,
Which are the aggressive nhl types,
What infections are associated wi...
16  cards
Nausea section
Dronabinol use,
3 types of emesis and time course,
Categories of emetic risk in chem...
26  cards
NSCLC
2 most common mutations in nsclc,
How does smoking induce carcinoge...,
Effect of screening for lung cancer
213  cards
multiple myeloma
Rvd is,
Newly approved agents for mm,
Bortezomib moa
211  cards
Myeloid sarcoma
How is myeloid sarcoma classified,
What is myeloid sarcoma,
Relation of myeloid sarcoma to bo...
6  cards
Response assessment
Pr per recist criteria 11 is,
Progressive disease per recist cr...
2  cards
NOACs
Xarelto renal dosing,
Best noac for renal failure,
What is bextriban approved for
3  cards
Neutropenia
Level at which you see increased ...,
Infection risk greatly increases ...,
Regimens where gcsf support is re...
5  cards
ONcology
When mastectomy is required over bct,
Screening required for ais,
Indications for adjuvant chemo in...
52  cards
Paroxysmal nocturnal hemoglobinuria
Prophylactic ac,
Association to know for boards,
Diagnosis
10  cards
Neuroendocrine tumors
Management of low grade net,
Management of high grade net,
Who grading is based on
12  cards
Neutropenic fever
Cause of fever in most neutropeni...,
Medication associated with reacti...,
When anc is expected to reach nad...
43  cards
oncology 3
Srs meaning,
Nivolumab mechanism,
Sbrt meaning
25  cards
ovarian cancer
Ovarian cancer mortality,
Brca pattern of inheritance,
Ovarian cancer and chemotherapy
22  cards
Pancreatic cancer
Breakdown of pancreatic cancer an...,
Rfs for pancreatic cancer,
Clinical significance of pancreat...
54  cards
Pancytopenia
Retic index cutoff indicating hyp...,
Bone marrow exam with anorexia an...
2  cards
oncology
Krukenberg tumor,
Leiomyosarcoma,
Tumor thrombus
49  cards
Pathology
How many segmentations does a nor...,
Neutrophil hypersegmentation occu...,
Differentiating teardrop cell tha...
6  cards
Oncology
How is cure defined,
Primary meaning,
Relative importance of pathologic...
3  cards
Performance status
What is ecog 0,
What is ecog 1,
What is ecog 2
8  cards
Plasmacytoma
Definition,
Location,
Term for plasmacytoma of soft tissue
12  cards
pharmacology
Lupron,
Bep use and components,
When mesna is required with cyclo...
12  cards
Plasma cell dyscrasia
0  cards
Passenger lymphocyte syndrome
Physiology
1  cards
Physical exam
Purpura vs petechia
1  cards
Paraneoplastic syndromes
Pthrp most common in which malign...
1  cards
Penile cancer
Surgery for penis referred to as
1  cards
Principles of oncology
Deescalation concept
1  cards
POEMS syndrome
Physiology,
Acronym stands for,
Mandatory major criteria for diag...
6  cards
Polycythemia Vera
Median survival of pv patients,
Possible transformations of pv,
What characterizes pv pathophysio...
11  cards
Pregnancy
When is risk of vte highest in pr...,
Why are pregnant patients hyperco...
2  cards
Pheochromocytoma
What is a paraganglioma,
Genetic syndromes associated with...,
Common locations of mets
3  cards
Portal vein thrombosis
Management of acute pvt,
Ac not to use why,
Patients in whom pvt occurs
17  cards
Plasma cell leukemia
Behavior,
Diagnostic criteria,
Overall survival
4  cards
Radiation Oncology
Most radiosensitive cancers,
Moderately radiosensitive cancers,
Radioresistant cancers
24  cards
Prophylaxis
Acyclovir dosing,
When pcp prophylaxis is indicated,
When hsv ppx is indicated
11  cards
Platelet disorders
What are the congenital qualitati...,
When to suspect qualitative plate...,
Clinical presentation in general
5  cards
Pulmonary nodules
Fdg avidity as measured by suv di...,
Fdg avidity differentiating moder...,
How do you determine baseline avi...
11  cards
Radiology
What is deauville score,
Pet uptake in thyroid gland,
Suv threshold that can routinely ...
6  cards
Post transplant lymphoproliferative disorder
Treatment
1  cards
Pure red cell aplasia
Lab features,
Causes of acquired prca
2  cards
Side effect management
Interventions being investigated ...,
Interventions being investigated ...,
Neuropathy caveat
29  cards
Prostate Cancer
Medications with survival benefit...,
What are the aggressive variant p...,
Abiraterone mechanism
87  cards
Renal cell carcinoma
Rcc response to chemo,
Stauffer syndrome,
Stage of presentation most common...
105  cards
Prostate cancer II
Mans lifetime risk of developing pc,
Percentage of patients who develo...,
Average time of onset of castrate...
77  cards
Rovira clinic
Driver mutations to test for in n...,
Durvulumab mechanism,
Consolidation chemotherapy
25  cards
Protein S deficiency
Function of protein s,
Causes of false positives in prot...
2  cards
Smoldering multiple myeloma
Normal k l ratio,
Management of high risk smm,
Management of low or intermediate...
5  cards
Superior vena cava syndrome
Most common malignancies causing ...
1  cards
Rectal cancer
Pelvic extenteration,
Management of locally advanced re...,
Crm refers to
16  cards
Sinusoidal obstruction syndrome
Drugs that can cause sos,
Treatment
2  cards
Research
What are the pembro trials typica...,
What are the nivo trials typicall...,
What is efs
11  cards
sarcoma
Synovial sarcoma systemic regimens,
Soc for osteogenic osteosarcoma,
First line chemotherapy for osteo...
20  cards
Small cell lung cancer
Sclc vs nsclc in terms of doublin...,
Sclc chemo and radiosensitivity,
Typical clinical course
70  cards
Study design/research
Phase i study objective design,
Basket trial concept,
Phase ii study objective design
5  cards
Testicular Cancer
Presentation,
Tumor markers to test for as part...,
Premalignant condition associated...
117  cards
Thalassemia
At what level of mcv should you t...,
Hemoglobin s beta thalassemia ele...,
Hemoglobin e pathophys
23  cards
Terminology
Definitive,
Terminology for someone discontin...,
Term for real progression
72  cards
Stem cell transplant
General physiology of conventiona...,
How do you mobilize progenitor cells,
Auto transplant indications
4  cards
Sickle cell disease
Indications for transfusion in scd,
Secondary cva prevention in scd,
Acute chest syndrome presentation
33  cards
Supratherapeutic INR
Management of supra therapeutic i...,
Inr 10 no bleeding,
Management of supratherapeutic in...
4  cards
Thyroid cancer
Histologic variants of thyroid ca...,
Effect of gender as rf for thyroi...,
How thyroid cancer is usually found
52  cards
Thrombocytopenia
Most common cause of drug induced...,
What thrombophilias can you test ...,
At what level of thrombocytopenia...
14  cards
T cell lymphoproliferative disorders
Clinical features of t large gran...,
Preferred initial therapy for cd3...
2  cards
Thymoma
Paraneoplastic syndrome classical...,
Most common presentation,
Most common site of metastatic di...
4  cards
TLS
Treatment,
Labs consistent with tls,
Tls prophylaxis
15  cards
Transfusion Reactions
Presentation of febrile non hemol...,
Ahtr presentation,
How does a urticarial transfusion...
39  cards
T-cell Lymphoma
What are the peripheral t cell ly...,
Most common subtypes of ptcl,
General prognosis of peripheral t...
8  cards
Large cell neuroendocrine carcinomas (LCNEC)
0  cards
Uremic platelet dysfunction
Treatment
1  cards
CINV
High emetic risk ppx,
Emetic risk categories
3  cards
Transfusional iron overload syndrome
Most common settings,
Number of transfusions it require...,
How to quantify
10  cards
Thrombocytopenia and anticoagulation
Relation of thrombocytopenia and vte
1  cards
T-ALL
Clinical features of t all at pre...,
Drug used for unresponsive or rel...,
Markers
3  cards
Thrombotic microangiopathy
What is the relationship between ...,
What does maha mean,
Drugs associated with drug induce...
3  cards
Thrombophilia
What are the inherited thrombophi...,
Inheritance patterns of the inher...,
Liver disease and risk of thrombosis
7  cards
Transfusion medicine
How is cryo obtained,
What is aphaeresis,
Pathogen reduction technology
32  cards
TTP
Lab features of ttp,
Signs symptoms of ttp,
General progress for working up s...
22  cards
Fundamental
Is cr high or low with targeted t...,
Why give the best drug frontline
2  cards
NLPHL
Early stage treatment,
Immunophenotype of nlphl,
Nlphl histology
3  cards
sequencing
Tet2 seen in what,
When will payers cover ngs
2  cards
Von Willebrand Syndrome
Treatment options for perioperati...,
How desmopressin treats vws,
Lysteda generic name
40  cards
Waldenstrom Macrolgobulinemia
Waldenstrom s basic pathophysiology,
Presentation,
Disease associated with waldenstroms
22  cards
MALT lymphoma
Translocation associated with dec...
1  cards
Classical Heme
Factor deficiencies associated wi...,
Factor deficiency associated with...
2  cards
Infusion reactions
2  cards
High yield ITE
Sarcoma imaging role of pet mri,
Staging workup of sarcoma of extr...,
Nht with demonstrated mfs benefit...
29  cards

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Hematology, oncology

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