Lymphoma Flashcards
1
Q
Molecular basis of richter’s transformation in FL
A
More aggressive subclone emerges with loss of follicular pattern
2
Q
Term for disease outside of lymph nodes in lymphoma
A
Extranodal disease
3
Q
Most common pathogen in HIV-associated lymphoma
A
EBV
4
Q
Management of primary testicular lymphoma
A
R-CHOP for 6 cycles, w/ CNS prophylaxis with high dose MTX, followed by scrotal irradiation
5
Q
When you should be most concerned about hep b reactivation
A
Anti-CD20 therapy
6
Q
Characteristic lymphocytes of splenic marginal zone lymphoma
A
villous lymphocytes
7
Q
What malignancies can transform to DLBCL? Ie what does Ritcher’s apply to?
A
CLL and Hairy cell leukemia
