Engraftment syndrome Flashcards
1
Q
Clinical features
A
fever + maculopapular rash + early post transplant period 1-2 weeks after auto HCT (more rarely after allo’s)
2
Q
Other clinical features
A
variable presence of dyspnea + weight gain + diarrhea + altered mental status. pulmonary manifestations (bilateral ground-glass opacification, hilar or peribronchial consolidation, and thickening of interlobular septa, pleural effusions)
3
Q
Pathophysiology
A
- neutrophil recovery causes release of proinflammatory cytokines
4
Q
treatment
A
steroids
