Prototype Drug Unit 5 & 7- Acyclovir

Question 1

Therapeutic classification

Answer 1

Antiviral for herpesvirsuses

Question 2

Pharmacologic classification

Answer 2

Nucleoside (Deosyguanosine) analog

Question 3

Therapeutic effects and uses

Answer 3

Mostly used to treat herpes because HIV and AIDS have developed a resistance to the drug.

Question 4

Mechanism of action

Answer 4

Inhibits viral replications of enzymes. Once the acyclovir is inserted into the growing DNA chain, viral DNA synthesis is stopped, and then the replications ceases.

Question 5

Adverse effects

Answer 5

Nausea, vomiting, diarrhea, headache, pain, inflammation at injection sites

Question 6

Contraindications

Answer 6

Monitor people with kidney problems. Lower dose and encourage lots of fluids in people with crystalluria

Question 7

Drug interactions

Answer 7

Probenecid, zidovudine, and additive nephrotoxicity if taken with aminoglycosides