Prototype Drug Unit 5 & 7- Acetominophen (Tylenol)

Question 1

Therapeutic classification

Answer 1

Nonopioid analgesic, antipyretic

Question 2

Pharmacologic classification

Answer 2

Para-aminophenol derivative

Question 3

Therapeutic effects and uses

Answer 3

relieves mild to moderate pain but has no effect on inflammation. Used for osteoarthritis of the hip or knee, dysmenorrhea, dental procedures, headache, and myalgia. Used for fevers. It is okay for infants, children, and adolescents who have flulike symptoms or chickenpox

Question 4

Mechanism of action

Answer 4

Inhibits COX in the CNS but not in peripheral tissues. Goes directly to the heat-regulating center of the hypthalamus to produce peripheral vasodilation, sweating, and dissipation of heat.

Question 5

Adverse effects

Answer 5

Anorexia, nausea, vomiting, dizziness, lethargy, diaphoresis, chills, epigastric or abdominal pain, and diarrhea.

Question 6

Black Box Warning

Answer 6

Can cause severe liver injury and may cause serious allergic reactions with symptoms of angioedema (swelling from the throat up), difficulty breathing itching, rash

Question 7

Contraindications

Answer 7

Allergic to it, renal impairment

Question 8

Drug interactions

Answer 8

Alcohol increases hepatotoxicity (kill the liver)

Question 9

Herbal/ food interactions

Answer 9

Caffeine will enhance the analgesic effects. Hepatotoxicity occurs when used with echinacea