TERMS

Question 1

a state in which the individual in incapable of developing an immune response to a specific antigen

Answer 1

immunologic tolerance

Question 2

a lack of responsiveness to an individuals own antigens

Answer 2

self tolerance

Question 3

clonal depletion of self reactive T and B lymphocytes during their maturation in lymphoid organs (thymus, bone marrow); apoptosis occurring during development in utero

Answer 3

central tolerance

Question 4

back up systems exist to destroy or control any self reactive T cells that escape central clonal depletion

Answer 4

peripheral tolerance

Question 5

what is this type of peripheral tolerance?

activation induced cell death (apoptosis)

Answer 5

clonal deletion

Question 6

what is this type of peripheral tolerance?

prolonged or irreversible functional inactivation of lymphocytes induced by encounter with antigens under certain conditions

Answer 6

clonal anergy

Question 7

what is this type of peripheral tolerance?

suppressor T cells exist which can down regulate the function of auto reactive t cells

Answer 7

peripheral suppression by T cells