HIGH YIELD II Flashcards
the tumor margin and contour that is permeative and ill defined is?
malignant
more common than primary bone neoplasms?
metastatic
associated with Gardners syndrome?
osteoma
<2 cm in greatest dimension
femur and tibia most common
relieved by ASA
rim of sclerotic bone at edge with nidus
osteoid osteoma
histologically and radiographically identical to OO
> 2 cm
vertebral column most common site
not relieved by ASA
osteoblastoma
malignant mesenchymal neoplasm; 2nd most common malignant bone tumor
most common site of metastasis is the lungs via hematogenous spread
note: secondary arises from pagets disease and comes from osteochondroma
knee is most common location, codmans triangle, osteoid produced by malignant cells
osteosarcoma, note that knee is most common
exostoses
benign
morphology: hyaline cartilage, arise from metaphysis, near growth plate of long bones, bony projections anchored to cortex
osteochondroma
benign, mature hyaline cartilage
small bones of hands and feet
Ollie disease and maffucci syndrome can occur
chondroma (enchondroma)
rare, benign tumor
young patients, 2nd decade
epiphysis of proximal humerus and distal femur
highly cellular
chondroblastoma
malignant neoplasm in which mesenchymal cells produce cartilaginous matrix
skeletal distribution dominant in: shoulder pelvis proximal femur ribs vertebrae
assoc with many chondromas
***blue gray cut surface
chondrosarcoma
normal trabecular bone replaced by proliferation of fibrous tissue and disorderly islands of malformed bone
uncommon, benign localized monostotic polystotic polystotic disease w/ endocrine abnormalities (mccune Albright)
radiolucent
surrounded by thin layer of sclerotic bone
irregular, curvilinear islands of woven bone
fibrous dysplasia
benign but locally aggressive
3-5th decade
epiphyses of long bones, distal femur, proximal tibia
pain, swelling, pathologic fx
radiolucent, solitary, erode through cortex, multinucleate giant cells
giant cell tumor of bone
malignant, small round blue cell tumor
peaks in 2nd decade, arises within cavity in diaphysis of long bone, sites are femur, tibia, and pelvis
painful, enlarging masses, onion skin, periosteal Ron, 75% 5 yr survival
uniform, small, round blue cells; cytoplasm scant, no osteoid production, CD99 positive
Ewing sarcoma