HIGH YIELD III Flashcards
what are the major serum proteins?
albumin alpha, beta and gamma globulins ceruloplasmin alpha fetoprotein coagulation proteins C & S
major osmotic colloid in plasma as well as transport protein made in liver?
albumin
produced by beta lymphocytes
-total gamma globulin levels rise in most chronic liver disease
gamma globulins
produced mainly in hepatocytes
-alpha1 antitrypsin for emphysema and cirrhosis
alpha and beta globulins
copper containing serum glycoprotein made in liver
levels low in?
ceruloplasmin
Wilsons disease
severe hepatocellular disease
synthesized by embryonic hepatocytes and fetal yolk sac (big liver guy?)
levels rise in?
alpha fetoprotein
primary hepatocellular carcinoma
synthesized by the liver with exception of factor VIII,
synthesizes antithrombin III, protein C & S?
6 hrs for?
5 hrs for?
measurement of clotting factors is single best acute measurement for?
coagulation protein
factor VII
fibrinogen
hepatic fxn, (acute liver disease)
collectively measures II, V, VII & X
elevated in?
prothrombin time
hepatitis and cirrhosis, vit K deficiency
produced by intestinal bacteria when protein metabolized; readily enters portal circulation
transformed to urea in liver
ammonia