HIGH YIELD Flashcards
since non neoplastic bone diseases affects the skeleton what is the function of the skeletal system?
framework of body size and shape
mechanical support for mvmt and protection
mineral homeostasis
environment for hematopoiesis
major cells involved in skeletal mineralization?
osteoprogenitor cells
osteoblasts
osteocytes
osteoclasts
what are the matrix proteins?
majority type I collagen
woven bone present in adults means?
pathology
- fracture
- site of infection
- producing tumors
lamellar bone is deposited more slowly so is it stronger or weaker than woven bone?
stronger
4 types of lamellar bone?
cortex
- concentric
- circumferential
- interstitial
bone trabecular
-trabecular type (cancellous)
what are the two types of bone formation?
intramembranous formation
-flat bones like cranium from mesenchyme
enchondral formation
-cartilage model
what are the diseases of the abnormal matrix?
osteogenesis imperfecta
osteoporosis
mucopolysaccharidoses
diseases of osteoclast dysfunction?
osteopetrosis
pagets disease of bone
disease of abnormal mineral homeostasis?
osteomalacia
hyperparathyroidism
renal osteodystrophy
types of fractures?
complete vs incomplete(greenstick) closed compound comminuted displaced pathologic spiral
other types of non neoplastic bone pathology?
osteonecrosis
osteomyelitis
