HEPATITIS Flashcards
name this hepatitis?
pircornaviridae; 27 nm, non enveloped RNA virus
fecal oral transmission
replicates in hepatocyte cytoplasm
-mild, acute, and self limited
jaundice greatest at >14 years (70-80%)
hep A
name this hepatitis?
partial dsDNA hepadnavirus
parenteral(blood borne) transmission
hep B
name this hepatitis?
ssRNA, 50 micro meters, flavivirus
blood borne
#1 reason for liver transplant in adults
-chronic infection leading to cirrhosis
hep C
name this hepatitis?
ssRNA, defective virus
blood borne
requires presence of HBV to become infectious
hep D
name this hepatitis?
small ssRNA calcivirus
fecal oral transmission
no chronic hepatitis or carrier state that can cause fulminant hepatitis, esp in pregnant women
hep E
what are the other viruses?
Herpes
- EBV
- CMV
- HSV
Adenovirus
what is this herpes virus?
liver affected in >90%
-elevated aminotransferases
post transplant
rare chronic hep/cirrohsis
diagnosis-serology, liver biopsy
EBV
what is this herpes virus?
healthy patients generally self limited-no chronic liver disease
immunocompromised affected
-most important pathogen in transplanted patients
diagnosis-viral load, biopsy
CMV
what is this herpes virus?
usually immunocompromised
rapidly progressive
dx: biopsy, culture
HSV
