TERMS Flashcards
waste product of protein/AAA metabolism
ammonia converted to urea in the liver
measured as BUN
filtered by the glomerulus and reabsorbed by the tubules, no secretion
what is this nitrogen waste clearance?
urea
what is this nitrogen waste clearance?
converted to urea by the liver
toxic levels occur in some disease states
ammonia
what is this nitrogen waste clearance?
fxn of lean body mass
derived from nonenzymatic interconversion of creatine in skeletal muscle
freely filtered by glomerulus, no reabsorption, partial tubular secretion
creatinine
what is this nitrogen waste clearance?
derived from the oxidation of purine bases
uric acid
what is this test of renal function?
serum/plasma concentration of nitrogen is proportional to serum/plasma concentration of urea
crude measure of renal fxn with levels increasing with decreasing renal fxn
blood urea nitrogen
what is this test of renal function?
this is a serum/plasma concentration of creatinine with better measure of renal fxn than BUN and increases with decreasing renal fxn
creatinine
this is a program to reduce interlab variation in creatinine assay calibration, giving more accurate estimates of GFR
creatinine standardization program
what is this test of renal function?
this parallels the GFR w/ reference range of 125 mL/min and corrects for non renal factors influencing serum/plasma creatinine
better measure of renal fxn than BUN or creatinine
creatinine clearance
what is this test of renal function?
normally scant amount of protein in urine, 150 mg excreted daily
detection of an abnormal amount in the urine is a reliable indication of renal disease
24 hr wait time
urine protein
syndrome characterized by heavy proteinuria, low serum albumin, generalized edema, and increased serum lipids
protein excretion is typically 3.5 g/24 hrs
nephrotic syndrome
the actual injury occurs to the kidney, either biomechanically or histologically
acute kidney injury (AKI)
encompasses all causes including prerenal azotemia and obstructive uropathy
acute renal failure (ARF)
this disease occurs with increased concentration of serum/plasma urea and/or creatinine
clinical symptoms not implied with many causes
azotemia
name this type of azotemia?
trauma
hemorrhage
severe dehydration
pre renal azotemia
name this type of azotemia?
chronic glomerulonephritis
bilateral chronic pyelonephritis
acute tubular necrosis (ATN)
renal azotemia
name this type of azotemia?
ureteral/urethra obstruction
obstructing tumors of the bladder, congenital defects, prostatic obstruction
post renal azotemia
name this disease, when you have azotemia + clinical S&S + biochemical abnormalities, resulting from marked reduction in overall renal fxn, and metabolic abnormalities
fatigue, lassitude
psychosis
anemia
peripheral neuropathy
uremia
synthesized in the supraoptic nuclei of the hypothalamus, passes to the posterior pituitary, where it is stored and released
stimulates water reabsorption in distal tubules
concentrates urine
ADH
total number of moles of a solute in solution after dissociation
osmole
the number of osmoses of solute for every 1000g of solution
osmolality
number of osmoles of solute for every liter of solution
osmolarity
measure of water balance
osmolality
pituitary insufficiency is what type of diabetes insipidus?
central
renal insensitivity is what type of diabetes insipidus?
renal
this is due to the inappropriate secretion of ADH?
SIADH
