HIGH YIELD-DEVELOPMENTAL DISEASE

Question 1

ventral buds fail to rotate properly

pancreas encircles duodenum, may constrict

assoc with down syndrome

Answer 1

annular pancreas

Question 2

most common congenital anomaly (5-10%)

classic type results from lack of fusion of dorsal and ventral buds

predispose to pancreatitis

Answer 2

pancrease divisum

Question 3

normal pancreactic tissue found in abnormal places

no anatomic continuity with pancreas

found at any age
obstructions, ulcerations, bleeding
GI tract, esp. stomach
lung, umbilicus, spleen omentum

Answer 3

heterotropic pancreas

Question 4

one of the most common hereditary disorder in whites; autosomal recessive

CFTR gene
-functions as a chloride ion channel

obstruction of exocrine ducts by thick secretions

Answer 4

cystic fibrosis

Question 5

maternal diabetes
caused by hyperinsulinemic hypoglycemic
requires partial pancreatectomy

Answer 5

islet cell hypertrophy and hyperplasia