HIGH YIELD-CIRRHOSIS Flashcards

1
Q

top 10 causes of death in the west, not a specific disease but an end stage of many diseases

A

cirrhosis

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2
Q

what are the characteristics of cirrhosis?

A

bridging fibrous septae
regenerative parenchymal nodules
diffuse
reorganized vascularity

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3
Q

progressive cirrhosis leads to increased risk to developing?

A

hepatocellular carcinoma

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4
Q

what is the etiology?

A
alcohol
viral
biliary disease
primary hemochromatosis
cryptogenic
other: Wilsons disease
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5
Q

pathogenesis?**

A

Ito cells stimulated by cytokines to become myofibroblastic cells creating collagen excess; periportal fibrosis occurs toward central veins (bridging fibrosis)

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