CLINICAL SYNDROMES Flashcards
clinical syndromes present as what types of infection?
acute
chronic
types of acute infection?
acute hepatitis
fulminant hepatitis
types of chronic infection?
chronic hepatitis
the hepatocyte injury presents as how for acute infection?
ballooning
macrophage aggregates
apoptosis
disarray
this acute infection is an asymptomatic, fulminant hepatitis (liver failure)
acute hepatitis
what are the 4 phases of infection?
incubation
preicteric
icteric
convalescent
what are the liver function tests for acute hepatitis, specifically:
hepatocellular injury
biliary injury
AST/ALT
ALP, GGT
what are the true measures of function for acute hepatitis?
bilirubin
albumin
prothrombin time
this acute infection is liver failure within 2-3 weeks (coagulopathy and mental changes due to encephalopathy)?
what is considered subfulminant?
fulminant hepatitis
3 months
this chronic infection is symptomatic?
lasts > 6months
hepatic complications
immune complex disease
#1 cause?
chronic hepatitis
HBV/HCV
major complications of chronic hepatitis?
persistent LFT elevation jaundice hepatocellular carcinoma cirrhosis liver failure
immune complex disease
pathology of chronic hep?
predominantly portal inflammation
- lymphocytes
- interface hepatitis
- fibrosis
